(function(){ var content_array=["

鍏充簬ORSERDU (elacestrant)<\/b><\/p> \n

缇庡浗閫傚簲鐥囷細<\/b>ORSERDU (elacestrant)锛�345 mg鐗囧墏锛岄€傜敤浜庢不鐤楁偅闆屾縺绱犲彈浣�(ER)闃虫€с€佷汉琛ㄧ毊鐢熼暱鍥犲瓙鍙椾綋2 (HER2)闃存€с€�ESR1<\/i>绐佸彉鏅氭湡鎴栬浆绉绘€т钩鑵虹檶涓旀帴鍙楄繃鑷冲皯涓€绉嶅唴鍒嗘硨鐤楁硶鍚庣柧鐥呭彂鐢熻繘灞曠殑缁濈粡鍚庡コ鎬ф垨鎴愬勾鐢锋€с€�<\/p> \n

鏈夊叧缇庡浗鐨勫畬鏁村鏂逛俊鎭紝璇疯闂�www.orserdu.com<\/a>銆�<\/p> \n

閲嶈瀹夊叏淇℃伅
<\/b> 璀﹀憡鍜屾敞鎰忎簨椤�<\/i><\/p> \n

琛€鑴傚紓甯�<\/i>锛氭湇鐢∣RSERDU鐨勬偅鑰呬腑楂樿儐鍥洪唶琛€鐥囧拰楂樼敇娌逛笁閰鐥囩殑鍙戠敓鐜囧垎鍒负30%鍜�27%銆� 3绾у拰4绾ч珮鑳嗗浐閱囪鐥囧拰楂樼敇娌逛笁閰鐥囩殑鍙戠敓鐜囧垎鍒负0.9%鍜�2.2%銆� 鍦ㄥ紑濮嬫湇鐢∣RSERDU涔嬪墠鍙婃湇鐢ㄦ湡闂村畾鏈熺洃娴嬭鑴傘€�<\/p> \n

鑳氳儙姣掓€�<\/i>锛氭牴鎹姩鐗╄瘯楠岀粨鏋滃強鍏朵綔鐢ㄦ満鍒讹紝瀵瑰瓡濡囦娇鐢∣RSERDU鍙兘瀵硅儙鍎块€犳垚浼ゅ銆� 鍚戝瓡濡囧拰鑲查緞濂虫€у憡鐭ュ鑳庡効鐨勬綔鍦ㄩ闄┿€� 寤鸿鑲查緞濂虫€у湪浣跨敤ORSERDU杩涜娌荤枟鏈熼棿鍙婃湯娆＄粰鑽悗1鍛ㄥ唴閲囧彇鏈夋晥閬垮瓡鎺柦銆� 寤鸿鏈夎偛榫勫コ鎬т即渚ｇ殑鐢锋€ф偅鑰呭湪浣跨敤ORSERDU杩涜娌荤枟鏈熼棿鍙婃湯娆＄粰鑽悗1鍛ㄥ唴閲囧彇鏈夋晥閬垮瓡鎺柦銆�<\/p> \n

涓嶈壇鍙嶅簲<\/i><\/p> \n

鎺ュ彈ORSERDU娌荤枟鐨勬偅鑰呬腑鏈�12%鍑虹幇杩�涓ラ噸涓嶈壇鍙嶅簲<\/i>銆� 瓒呰繃1%鐨勬帴鍙桹RSERDU娌荤枟鎮ｈ€呯殑涓ラ噸涓嶈壇鍙嶅簲涓鸿倢鑲夐楠肩柤鐥�(1.7%)鍜屾伓蹇�(1.3%)銆� 鎺ュ彈ORSERDU娌荤枟鎮ｈ€呬腑鏈�1.7%鍑虹幇杩囪嚧鍛戒笉鑹弽搴旓紝鍖呮嫭蹇冭剰楠ゅ仠銆佹劅鏌撴€т紤鍏嬨€佹啯瀹ょ値鍜屾湭鐭ュ師鍥狅紙鍚�1鍚嶆偅鑰咃級銆傚寘鎷疄楠屽妫€鏌ユ寚鏍囧紓甯稿湪鍐咃紝ORSERDU寮曞彂鐨�
鏈€甯歌涓嶈壇鍙嶅簲(鈮�10%)<\/i>鍖呮嫭鑲岃倝楠ㄩ鐤肩棝(41%)銆佹伓蹇�(35%)銆佽儐鍥洪唶鍗囬珮(30%)銆佸ぉ闂ㄥ啲姘ㄩ吀姘ㄥ熀杞Щ閰跺崌楂�(29%)銆佺敇娌逛笁閰崌楂�(27%)銆佺柌鍔�(26%)銆佽绾㈣泲鐧藉噺灏�(26%)銆佸憰鍚�(19%)銆佽胺涓欒浆姘ㄩ叾鍗囬珮(17%)銆侀挔鍑忓皯(16%)銆佽倢閰搁厫鍗囬珮(16%)銆侀娆插噺閫€(15%)銆佽吂娉�(13%)銆佸ご鐥�(12%)銆佷究绉�(12%)銆佽吂鐥�(11%)銆佹疆鐑�(11%)鍜屾秷鍖栦笉鑹�(10%)銆�<\/p> \n

鑽墿鐩镐簰浣滅敤<\/i><\/p> \n

涓嶤YP3A4璇卞鍓傚拰\/鎴栨姂鍒跺墏鍚屾椂浣跨敤<\/i>锛氶伩鍏嶅己鎴栦腑CYP3A4鎶戝埗鍓備笌ORSERDU鍚屾椂浣跨敤銆� 閬垮厤寮烘垨涓瑿YP3A4璇卞鍓備笌ORSERDU鍚屾椂浣跨敤銆�<\/p> \n

鐗规畩浜虹兢鐢ㄨ嵂<\/i><\/p> \n

鍝轰钩<\/i>锛氬缓璁摵涔虫湡濡囧コ鍦ㄦ帴鍙桹RSERDU娌荤枟鏈熼棿鍜屾湯娆＄粰鑽悗1鍛ㄥ唴涓嶈繘琛屾瘝涔冲杺鍏汇€�
鑲濆姛鑳芥崯瀹�<\/i>锛氶伩鍏嶅涓ラ噸鑲濆姛鑳芥崯瀹�(Child-Pugh C)鎮ｈ€呬娇鐢∣RSERDU銆� 瀵逛腑搴﹁倽鍔熻兘鎹熷锛圕hild-Pugh B锛夋偅鑰呭噺灏慜RSERDU鍓傞噺銆�
ORSERDU瀵瑰効绉戞偅鑰呯殑瀹夊叏鎬у拰鏈夋晥鎬у皻涓嶇‘瀹氥€�<\/p> \n

濡傞渶鎶ュ憡鐤戜技涓嶈壇鍙嶅簲锛岃鑷寸數1-877-332-7961鑱旂郴Stemline Therapeutics, Inc.锛屾垨閫氳繃1-800-FDA-1088鎴�www.fda.gov\/medwatch<\/a>鑱旂郴FDA銆�<\/p> \n

鍏充簬缇庣撼閲屽凹闆嗗洟<\/b><\/p> \n