鍏充簬闃挎柉鍒╁悍鍦ㄤ钩鑵虹檶棰嗗煙鐨勭爺绌�<\/u><\/b><\/p> \n
闅忕潃瀵逛钩鑵虹檶鐢熺墿瀛︾殑鏃ョ泭浜嗚В锛岄樋鏂埄搴峰紑濮嬫寫鎴樺拰閲嶆柊瀹氫箟涔宠吅鐧岀殑鍒嗙被鍙婁复搴婃不鐤楁ā寮忥紝浠ユ彁渚涚粰鎮ｈ€呮墍闇€鐨勬洿涓虹簿鍑嗚€屾湁鏁堢殑娌荤枟鏂规銆傞樋鏂埄搴烽泟蹇冨媰鍕冿紝甯屾湜鏈夋湞涓€鏃ュ彲浠ユ秷闄や钩鑵虹檶杩欎竴鑷存鐥呭洜銆�<\/p> \n
闃挎柉鍒╁悍鐮斿彂浜嗕竴绯诲垪宸茶幏鎵规垨鏈夋湜鑾锋壒鐨勮嵂鐗╋紝閫氳繃澶氱鏈哄埗搴斿涔宠吅鐧岃偪鐦ゅ井鐜鐨勭敓鐗╁鏍锋€с€�<\/p> \n
鍑€熷痉鏇插Ε鐝犲崟鎶楋紝鐢遍樋鏂埄搴峰拰绗竴涓夊叡鑱斿悎寮€鍙戝拰鍟嗕笟鍖栫殑涓€绉嶉澏鍚慔ER2鐨勬姉浣撳伓鑱旇嵂鐗╋紝闃挎柉鍒╁悍鍜岀涓€涓夊叡鐨勭洰鏍囨槸鏀瑰杽鍏堝墠娌荤枟鐨凥ER2闃虫€у拰HER2浣庤〃杈捐浆绉绘€т钩鑵虹檶鐨勭粨鏋滐紝骞舵鍦ㄦ帰绱㈠叾鍦ㄦ洿鏃╃嚎涔宠吅鐧屾偅鑰呬腑鐨勬不鐤楁綔鍔涖€�<\/p> \n
鍦℉R闃虫€т钩鑵虹檶涓紝闃挎柉鍒╁悍缁х画鎸佺画渚濇墭鍩虹煶鑽墿姘熺淮鍙哥兢鍜屾垐鑸嶇憺鏋椾互鏀瑰杽鎮ｈ€呯殑棰勫悗锛屽苟鏃ㄥ湪閫氳繃 ngSERD camizestrant鍜孉KT婵€閰舵姂鍒跺墏capivasertib閲嶅HR闃虫€т钩鑵虹檶娌荤枟銆傚悓鏃讹紝闃挎柉鍒╁悍涓庣涓€涓夊叡鍚堜綔锛屾鍦ㄦ帰绱㈠拰璇勪及 TROP2闈跺悜ADC datopotamab deruxtecan鐨勭枟鏁堛€�<\/p> \n
PARP鎶戝埗鍓傚ゥ鎷夊笗鍒╂槸涓€绉嶉澏鍚戞不鐤楅€夋嫨锛屽凡鍦ㄦ惡甯RCA鑳氱郴绐佸彉鐨凥ER2闃存€ф棭鏈熷拰杞Щ鎬т钩鑵虹檶鎮ｈ€呬腑寮€灞曚复搴�鐮旂┒<\/span>骞惰幏寰楅槼鎬х殑鐮旂┒缁撴灉銆傞樋鏂埄搴峰拰榛樻矙涓滃皢鎸佺画鎺ㄥ姩濂ユ媺甯曞埄鍦˙RCA鑳氱郴绐佸彉鐨勬棭鏈熷拰杞Щ鎬т钩鑵虹檶鎮ｈ€呬腑鐨勬不鐤楀彲鍙婃€с€傛澶栵紝闃挎柉鍒╁悍绗簩浠ARP鎶戝埗鍓侫ZD5305涔熷凡缁忚繘鍏ヤ复搴婄爺绌讹紝鏃ㄥ湪杩涗竴姝ユ帰绱ARP鎶戝埗鍓傚湪涔宠吅鐧屼腑娌荤枟娼滆兘銆�<\/p> \n
涓轰簡婊¤冻涓夐槾鎬т钩鑵虹檶鎮ｈ€呭鏇村娌荤枟閫夋嫨鐨勮揩鍒囬渶姹傦紝闃挎柉鍒╁悍姝ｅ湪璇勪及AKT婵€閰舵姂鍒跺墏capivasertib涓庡寲鐤楄仈鐢ㄣ€乨atopotamab deruxtecan鍗曡嵂鎴栦笌搴︿紣鍒╁挨鍗曟姉鑱旂敤鐨勬不鐤楁晥鏋溿€傛澶栵紝涔熷湪璇勪及搴︿紣鍒╁挨鍗曟姉涓庡ゥ鎷夊笗鍒┿€佸痉鏇插Ε鐝犲崟鎶楃瓑涓庡叾浠栬偪鐦よ嵂鐗╄仈鍚堢敤鑽殑鐤楁晥鍜屽畨鍏ㄦ€с€�<\/p> \n
鍏充簬闃挎柉鍒╁悍<\/u><\/b><\/p> \n
闃挎柉鍒╁悍锛圠SE\/STO\/Nasdaq: AZN锛夋槸涓€瀹剁瀛﹁嚦涓婄殑鍏ㄧ悆鐢熺墿鍒惰嵂浼佷笟锛屼笓娉ㄤ簬鐮斿彂銆佺敓浜у強钀ラ攢澶勬柟绫昏嵂鍝侊紝閲嶇偣鍏虫敞鑲跨槫銆佺綍瑙佺梾浠ュ強鍖呮嫭蹇冭绠¤偩鑴忓強浠ｈ阿銆佸懠鍚稿強鍏嶇柅鍦ㄥ唴鐨勭敓鐗╁埗鑽瓑棰嗗煙銆傞樋鏂埄搴峰叏鐞冩€婚儴浣嶄簬鑻卞浗鍓戞ˉ锛屼笟鍔￠亶甯冭秴杩�125涓浗瀹讹紝鍒涙柊鑽墿鎯犲強鍏ㄧ悆鏁扮櫨涓囨偅鑰呫€傛洿澶氫俊鎭紝璇疯闂�www.astrazeneca.com<\/span><\/u><\/a>銆�<\/p> \n
鍏充簬闃挎柉鍒╁悍涓浗<\/u><\/b><\/p> \n
澹版槑锛氭湰鏂囨秹鍙婃湭鍦ㄤ腑鍥借幏鎵圭殑浜у搧鎴栭€傚簲鐥囷紝闃挎柉鍒╁悍涓嶆帹鑽愪换浣曟湭鑾锋壒鑽搧\/閫傚簲鐥囩殑浣跨敤銆�<\/p> \n